产品信息： Form White solid Primary Target brain calmodulin-dependent phosphodiesterase Primary Target IC50 10 nM Secondary target skeletal muscle sarcoplasmic reticulum Ca2+-ATPase (Ki = 60 nM) Cell permeable 是的 Purity ≥95% by HPLC Chemical formula C31H23Cl7N2O CAS number 57265-65-3 Storage -20°C Ship Ambient Temperature Only Standard Handling 产品说明： A cell-permeable calmodulin antagonist. At least 150 times more potent than Trifluoperazine (Cat. No. 642150) as an inhibitor of brain calmodulin-dependent phosphodiesterase (IC50 = 10 nM). An inhibitor of voltage-gated Ca2+ channels. Stimulates the release of nitric oxide in neuroblastoma cells. Also acts as a strong non-competitive inhibitor of skeletal muscle sarcoplasmic reticulum Ca2+-ATPase (Ki = 60 nM). Known to prolong cardiac refractoriness in vivo. Note: easily adheres to glass in aqueous solution.