Calcineurin Autoinhibitory Peptide Specific calcineurin inhibitor. Corresponds to the C-terminal domain (residues 457-482) of the calmodulin-binding domain of calcineurin (PP2B). Inhibits Mn2+-stimulated calcineurin activity (IC50 = 10 µM using 32P-myosin light chain as a substrate) but has no effect on Ni2+-stimulated enzyme activity. Does not inhibit CaM kinase II, protein phosphatase 1 or 2A. 产品信息 Peptide Sequence H-Ile-Thr-Ser-Phe-Glu-Glu-Ala-Lys-Gly-Leu-Asp-Arg-Ile-Asn-Glu-Arg-Met-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro-OH Form Lyophilized Formulation Supplied as a trifluoroacetate salt. Primary Target Mn2+-stimulated calcineurin activity Primary Target IC50 10 µM using 32P-myosin light chain as a substrate Molar mass 2930.4 Hygrocopic 是的 Purity ≥97% by HPLC Sold on the basis of peptide content 是的 Solubility H2O Chemical formula C124H205N39O39S2 商店和运输信息 Storage -20°C Ship Ambient Temperature Only Standard Handling