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Anthrax Protective Antigen, Bacillus anthracis, Recombinant, B. anthracis
Recombinant, Bacillus anthracis anthrax protective antigen expressed in a specialized strain of B. anthracis. One of the three protein components of Anthrax toxin, protective antigen (PA) is the central moiety that mediates the entry of lethal factor and edema factor into the target cell. PA binds to the cell surface via a type I membrane protein with a von Willebrand factor A domain called anthrax toxin receptor. After proteolytic activation to a 63 kDa fragment, PA self-associates to form a heptameric cation-selective, voltage-gated membrane channel.
产品信息
Form Lyophilized
Formulation Lyophilized from 50 mM NaCl, 5 mM HEPES, pH 7.5.
Molar mass 83000
Purity Single major band by SDS-PAGE. Several smaller minor components are apparent that may represent cleavage fragments of the PA.
Solubility H2O
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling
Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
End use certificate To purchase this product, the completion of a "Select Agent Declaration" and/or "End-Use Certificate" is required. Once your sales order is placed, our Regulatory Specialist will be contacting the end-user of this product to complete the required form(s). Please ensure to provide the customer service representative with the end-user's name, telephone number, fax number and e-mail address to prevent delivery delays. (Note: the completed form must be returned within five (5) business days from receipt and will be valid for one year from the date of signing.) |