Angiogenesis Inhibitor (Z,E)-3-(Imidazol-4-ylmethylene)indolin-2-one A cell-permeable indolinone compound that displays anti-angiogenesis properties (30% inhibition of control at 10 µM in an in vitro rat aortic ring model ) with a potency that is comparable to that of SU5416 (Cat. No. 676487; 22% inhibition of control at 10 µM). Acts as a moderate ATP-competitive inhibitor of hEGF-R tyrosine kinase activity (54% inhibition at 10 µM). 产品信息 Form Yellow solid Primary Target hEGF-R tyrosine kinase activity Primary Target IC50 54% inhibition at 10 µM Molar mass 211.2 Protect from Light 是的 Packaged under inert gas 是的 Cell permeable 是的 ATP Competitive 是的 Purity ≥95% by HPLC Solubility DMSO Chemical formula C12H9N3O CAS number 186611-44-9 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Carcinogenic / Teratogenic