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产品说明
A bicyclic diterpenoid lactone that displays anti-viral, anti-inflammatory, anti-apoptotic, and anti-hyperglycemic properties. Acts as an irreversible antagonist of NF-κB and AP-1 (IC50 ≤ 15 µM) activation, and prevents in vitro and in vivo T cell activation. Exerts no effect on IκBα degradation, p50 and p65 nuclear translocation. Inhibits iNOS and Mac-1 expressions and ROS production, and prevents endotoxin shock in mouse model. Further, reported to activate PI 3K/Akt pathway.
产品信息
Form Off-white solid
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥95% by TLC
Chemical formula C20H30O5
RTECS LU3490750
CAS number 5508-58-7
Merck USA index 14, 633
Storage +2°C to +8°C
Ship Ambient Temperature Only
Carcinogenic / Teratogenic |