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Substance P
Neuropeptide found in high concentrations in the gut. When released from afferent nerves, causes a neurogenic inflammatory response, including mast cell degranulation. Induces Ca2+ mobilization. Reported to activate Goα, Gq/11α, and Gsα subunits in CHO cells via activation of substance P receptors. Also reported to induce superoxide production in neutrophils.
Peptide Sequence H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
Form White solid
Formulation Supplied as a trifluoroacetate salt.
Molar mass 1347.6
Hygrocopic 是的
Purity ≥96% by HPLC
Sold on the basis of peptide content 是的
Solubility 5% Acetic Acid
Chemical formula C63H98N18O13S
CAS number 33507-63-0
Merck USA index 14, 8863
Storage -20°C
Ship Ambient Temperature Only
Standard Handling |