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CALPEPTIN

产品编号: 03-34-0051-5MG     查看说明书
产品名称: CALPEPTIN  .0   订购此产品 
供应商: Merck
规格: 5MG
目录价: 1,094.00
库存状态: 3周到货
CAS编号: 117591-20-5
应用范围: 蛋白酶抑制剂
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 Calpeptin
Benzyloxycarbonylleucyl-norleucinal
A cell-permeable calpain inhibitor (ID50 = 52 nM for calpain-1; ID50 = 34 nM for calpain-2; ID50 = 138 nM for papain). Inhibits the Ca2+-stimulated cleavage of p35 to p25 by calpain. Modulates the processing of β-amyloid precursor protein to β-amyloid (Aβ). Promotes neurite elongation in differentiating PC12 cells. Prevents Ca2+-ionophore-induced degradation of actin binding protein and P235 in platelets. Inhibits myosin light chain phosphorylation in platelets stimulated by collagen, ionomycin, or thrombin. Inhibits the growth of estrogen receptor positive breast cancer cells
Peptide Sequence  Z-Leu-Nle-CHO 
Form  White to off-white solid 
Primary Target  calpain-1 
Primary Target IC50  52 nM 
Secondary target  calpain-2 (IC50 = 34 nM), papain (IC50 = 138 nM) 
Packaged under inert gas  是的 
Cell permeable  是的 
Purity  ≥94% by HPLC 
Chemical formula  C20H30N2O4 
CAS number  117591-20-5 
Storage  -20°C 
Ship  Ambient Temperature Only

 

保存条件: -20°C
说明书地址: 点击查看详细
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