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CD117 (c-Kit) [pYpY568/570] Rabbit pAb
c-Kit, also known as CD117 and stem cell factor receptor, is a 145 kDa transmembrane tyrosine kinase encoded by the c-Kit proto-oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Phosphorylation at tyrosine 703 of c-Kit allows binding of Grb2 and activation of the Ras --> Raf --> ERK1&2 signaling pathway.
Format⁄Formulation:
Unconjugated
Application:
WB
Reactivity: Human
Validated Application: Western Blot
Host: Rabbit
SubClass (Isotype): IgG
Clonality: Polyclonal
Target Gene: CD117 (c-Kit) [pYpY568/570]
Gene ID: 3815
Label or Dye: Unconjugated
Target Modification State: Phospho
Product Size: 10 blots
Purity or Quality Grade: Azide Free
Shipping Condition: Approved for shipment on Wet or Dry Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in freezer (-5 to -30°C). |