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Beta-Catenin [npaa 27-37] Mouse mAb (clone 8 E4)
The α-, β- and γ-catenins are cytoplasmic proteins mediating the interaction of Ca2+-dependent transmembrane adhesion molecules (cadherins) with the cytoskeletal network. The direct interaction of β-catenin with the cytoplasmic domain of cadherins plays a crucial role for cell-cell adhesion and signal transmission between neighboring cells.
Isotype: Mouse IgG1
Clone/PAD: b-Cat-8E4
Immunogen: Peptide containing amino acid residues 27-37, conjugated to KLH.
Specificity: The antibody specifically interacts with nuclear dephosphorylated β-catenin (90 kDa).
Reactivity: Cn, Hu, Ms
Applications: E, ICC, IHC (FFPE), WB
Reactivity: Human,
Canine,
Mouse
Validated Application: Immunocytochemistry,
ELISA,
Immunohistochemistry (FFPE),
Western Blot
Host: Mouse
Clonality: Monoclonal
Clone ID: 8 E4
Target Gene: Catenin beta [npaa 27-37]
Gene ID: 1499, 12387, 477032
Label or Dye: Unconjugated
Target Modification State: Non-Phospho
Product Size: 50 µL
Research Category: Signal Transduction
Shipping Condition: Dry Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in freezer (-5 to -30°C). |