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MDM2 [pS166] Rabbit Polyclonal Antibody
Murine double minute-2 (MDM2) is a 90 kDa Zinc finger oncoprotein that negatively regulates the transcriptional activation of p53 via ubiquitin-dependent proteasomal degradation. MDM2 is also shown to be phosphorylated on Ser166 and Ser188 in response to insulin-like growth factor-1 (IGF-1) in a phosphatidylinositide 3'-OH kinase-dependent manner.
Isotype:
Rabbit IgG
Immunogen:
Chemically synthesized phosphopeptide derived from the region of human MDM2 that contains serine 166.
Reactivity:
Hu, Ms
Applications:
WB
Reactivity: Mouse,
Human
Validated Application: Western Blot
Host: Rabbit
SubClass (Isotype): IgG
Clonality: Polyclonal
Target Gene: MDM2 [pS166]
Gene ID: 4193, 17246
Label or Dye: Unconjugated
Target Modification State: Phospho
Product Size: 100 µL
Shipping Condition: Approved for shipment on Wet or Dry Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in freezer (-5 to -30°C). |