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Cofilin [pS3] Rabbit Polyclonal Antibody
This rabbit anti-Cofilin [pS3] polyclonal antibody is specific to human, canine Cofilin [pS3] protein and expected to react with mouse and rat (not tested). AntiCofilin [pS3] polyclonal antibody recognizes the expressed product of the CFL1 gene. Cofilin is a 20 kDa actin-binding protein and a key regulator of actin dynamics involved in regulating lamellipodia formation, neurite extension, chemotaxis and tumor cell migration. Validated application for Cofilin [pS3] polyclonal antibody is Western blotting.
Applications: validated for Western blotting
Host species and isotype: rabbit IgG
Polyclonal Antibody Designation: human and canine [Mouse and rat cofilin (100% homologous) have not been tested, but are expected to react.]
Product size: 10 blots pack size
Cofilin is a 20 kDa actin-binding protein and a key regulator of actin dynamics involved in regulating lamellipodia formation, neurite extension, chemotaxis and tumor cell migration. Phosphorylation of cofilin by LIM kinase (LIMK1) on serine 3 mediates Rho-ROCK and Rac-PAK signaling pathways in regulating actin reorganization by inactivating cofilin, and blocking its ability to promote actin-filament disassembly.
Reactivity: Canine,
Human
Validated Application: Western Blot
Host: Rabbit
SubClass (Isotype): IgG
Clonality: Polyclonal
Target Gene: Cofilin [pS3]
Gene ID: 1072
Label or Dye: Unconjugated
Target Modification State: Phospho
Purification: Purified
Product Size: 10 blots
Shipping Condition: Approved for shipment on Wet or Dry Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in freezer (-5 to -30°C). |