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Cathepsin B Mouse mAb (clone 4B11)
Clone/PAD
4B11
Immunogen
Recombinant human pro-cathepsin B protein
Specificity
This antibody is specific for the cathepsin B (cathepsin B1, APP secretase, APPS) protein. On Western blots using human recombinant pro-cathepsin B, it identifies a target band at ~43 kDa. In case of mature cathepsin B, this antibody will identify a single chain at ~31 KDa, and for mature cathepsin B heavy chain it will identify two-chains at ~24-28 kDa. This antibody does not cross react with any other related lysosomal cystein proteinase (cathepsin L, H, K, S, V, W).
Reactivity
Reactivity has been confirmed with human recombinant pro-cathepsin B by Western Blotting, and with normal human kidney tissues by immunohistochemistry. Based on amino acid sequence homology, reactivity with rhesus monkey, rat, canine, bovine and swine is also expected.
Applications
Western blotting, immunohistochemistry (FFPE)
Reactivity: Human
Validated Application: Western Blot,
Immunohistochemistry (FFPE)
Host: Mouse
Clonality: Monoclonal
Clone ID: 4B11
Target Gene: CTSB
Gene ID: 1508
Label or Dye: Unconjugated
Purification: Affinity Purified
Product Size: 100 µg
Shipping Condition: Wet Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store at 2–8°C for up to one month, or at -20°C for long-term storage. Avoid repeated freezing and thawing. |