|
Claudin-1 Mouse Monoclonal Antibody (clone 2H10D10), Alexa Fluor® 488 Conjugate
Monoclonal antibody conjugated to Alexa Fluor® 488, and specific to Human , Rat , Canine and Mouse. This antibody is validated for use in WB, ICC/IF, ELISA and IP. Claudin-1 is encoded by the CLDN7, also known as CLDN7, claudin 7, CEPTRL2, CPETRL2, Hs.84359, claudin-1, Clostridium perfringens enterotoxin receptor-like 2, claudin 9. . The claudin (CLDN) superfamily consists of at least 18 homologous proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport, complexed with two other integral transmembrane proteins, occludin and junctional adhesion molecule.1 Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins interact directly with tight junction-specific, membrane-associated guanylate kinase homologues, ZO-1, ZO-2, and ZO-3, and indirectly with AF-6 and the myosin-binding molecule cingulin. These protein-protein interactions promote scaffolding of the tight
Reactivity: Human,
Rat,
Canine,
Mouse
Validated Application: Immunofluorescence,
Immunocytochemistry,
Immunoprecipitation,
ELISA,
Western Blot
Host: Mouse
SubClass (Isotype): IgG1
Clonality: Monoclonal
Clone ID: 2H10D10
Antibody Fragment: Whole Antibody
Target Gene: Claudin-1
Gene ID: 1366, 53674
Label or Dye: Alexa Fluor® 488
Excitation⁄Emission (nm): 495⁄519
Excitation Class: Visible
Emission Class: Visible
Purification: Purified
Concentration: 0.5 mg⁄ml
Color: Green
Form: Liquid
Neutralizing Antibody: No
Platform: Fluorescence Microscope
Product Size: 100 µg
Quantity: 1
Volume: 200 µl
Shipping Condition: Wet Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store reagents at 2-8°C. |