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Occludin Mouse mAb (OC-3F10)
This purified monoclonal mouse IgG1 κ antibody recognizes occludin.
Antibody Specifications:
• Validated in: Western Blot, Immunofluorescence, ELISA
• Isotype: Mouse IgG1 κ
• Clone: OC-3F10
• Reactivity: Human, Mouse, Rat, Canine
• Volume: 200 µl (0.5 mg/ml)
• Buffer: Phosphate buffered saline containing 0.1% sodium azide
The establishment and maintenance of tight junctions is crucial to both the development and normal functioning of most organs. These junctions play dual roles in the physiological functions of both epithelial and endothelial cells. Firstly, they function to create a barrier to the diffusion of solutes through the paracellular pathway. Secondly, they function as a boundary between the apical and basolateral plasma membrane domains to create and maintain cell polarity. Tight junctions (TJs) were first observed by electron microscopy over forty years ago and were defined as a set of continuous, anastomosing intramembrane strands. Yet, information on
Reactivity: Human,
Mouse,
Rat,
Canine
Validated Application: Immunofluorescence,
Western Blot,
ELISA
Host: Mouse
Clonality: Monoclonal
Clone ID: OC-3F10
Target Gene: Occludin
Gene ID: 100506658
Label or Dye: Unconjugated
Purification: Affinity Purified
Product Size: 100 µg
Research Category: Extracellular Matrix & Cell Adhesion
Shipping Condition: Wet Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in freezer (-5 to -30°C). |