|
Nitrotyrosine Monoclonal Antibody, Mouse (clone HM 11)
This mouse anti-Nitrotyrosine monoclonal antibody is specific to multiple Nitrotyrosine. The presence of nitrotyrosine has been detected in various inflammatory processes, including atherosclerotic plaques. Nitrotyrosine is formed in tissues in the presence of the active metabolite NO. Validated applications for nitrotyrosine monoclonal antibody are ELISA, immunoprecipitation, Western blotting and immunohistochemistry.
Applications: validated for ELISA, immunoprecipitation, Western blotting and immunohistochemistry
Host species and isotype: mouse IgG1
Clone ID of monoclonal antibody (mAb): HM11
Reactivity: multiple Nitrotyrosine
Product size: 100 µg pack size
The presence of nitrotyrosine has been detected in various inflammatory processes, including atherosclerotic plaques. Nitrotyrosine is formed in tissues in the presence of the active metabolite NO. Various pathways including the formation of peroxynitrite lead to nitrotyrosine production. It is still unknown whether nitration is merely a footprint of oxidative stress, an important pathway of nitric oxide metabolisms or a part of integral processes for maintaining cellular homeostasis.
Host: Mouse
Clone ID: HM11
Target Gene: Nitrotyrosine
Label or Dye: Unconjugated
Product Size: 100 µg
Purification: Purified
Validated Application: Immunohistochemistry,
Western Blot
Target Modification State: Nitrated
Shipping Condition: Wet Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in freezer (-5 to -30°C). |