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HER2 (c-erbB-2) Mouse Monclonal Antibody (clone TAB250), Concentrate
HER2, also known as the c-erbB-2 or Neu, is a member of the epidermal growth factor receptor family. This family of receptors are located on the plasma membrane and consist of an extracellular ligand binding domain that is connected to a large intracellular domain by a single transmembrane sequence. The cytoplasmic domain contains a tyrosine kinase that is activated by ligand-induced dimerization of the receptor. This family of receptors are important in regulating cell growth. Immunogen source: NIH3T3 cells transfected with the c-erbB-2.
Clone/PAD: TAB250
Immunogen: NIH3T3 cells transfected with the c-erbB-2 gene
Specificity: HER2 (c-erbB-2)
Applications: Analyte Specific Reagent
Validated Application: Immunohistochemistry (FFPE)
Host: Mouse
SubClass (Isotype): IgG1, kappa
Clonality: Monoclonal
Target Gene: HER2 (c-erbB-2)
Gene ID: 2064
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 1 mL
Shipping Condition: Wet Ice
Regulatory Statement: Analyte Specific Reagent. Analytical and performance characteristics are not established.
Store in refrigerator (2–8°C). |