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COX-2 Mouse Monoclonal Antibody (clone COX 229), Concentrate
This antibody reacts specifically with COX-2 protein. Cyclooxygenase (COX) is a membrane-bound enzyme, which has a molecular weight of 72 kDa. It is an enzyme that catalyzes the synthesis of cyclic endoperoxides from arachidonic acid to form prostaglandins (lipid-soluble, homone-like regulatory molecules). Two isoforms of COX have been identified and are known as COX-1 and COX-2. COX-2 is dimeric and is the inducible (i.e., sites of inflammation) isoform of cyclooxygenase.Positive tissue: Colon carcinoma.
Clone/PAD: COX 229
Immunogen: Synthetic peptide from human COX-2
Specificity: COX-2
Reactivity: Human
Applications: Immunohistochemistry (FFPE)
Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host: Mouse
SubClass (Isotype): IgG1, kappa
Clonality: Monoclonal
Target Gene: COX-2
Gene ID: 5743
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 0.5 mL
Shipping Condition: Wet Ice
Regulatory Statement: For In Vitro Diagnostic Use.
Store in refrigerator (2–8°C). |