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SKP2 (S-Phase Kinase-Associated Protein 2) Mouse Monoclonal Antibody (clone 2C8D9), Concentrate
SKP2 (S-phase Kinase-associated Protein 2) belongs to the family of F-box proteins that interact with the Cyclin A-Cdk2 complex. In tumor tissues, SKP2 is expressed widely, such as colon mucinous carcinoma, gastric adenocarcinoma, breast cancer, melanoma, prostate adenocarcinoma, with particularly higher expression on lung adenocarcinoma, lung squamous carcinoma, squamous carcinoma of cervix, endometrial carcinoma, ovary serous carcinoma and leiomyosarcoma. A recent study suggests that SKP2 plays a role in oncogenesis and is involved in the pathogenesis of lymphomas. Positive tissue: Breast cancer
Clone/PAD: 2C8D9
Immunogen: Recombinant human SKP2
Specificity: SKP2
Reactivity: Human
Applications: Immunohistochemistry (FFPE)
Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host: Mouse
SubClass (Isotype): IgG1
Clonality: Monoclonal
Target Gene: SKP2 (S-Phase Kinase-Associated Protein 2)
Gene ID: 6502
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 0.5 mL
Shipping Condition: Wet Ice
Regulatory Statement: For In Vitro Diagnostic Use.
Store in refrigerator (2–8°C). |