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TS (Thymidylate Synthase) Mouse Monoclonal Antibody (clone 4H4B1), Concentrate
Thymidylate Synthase (TS) catalyzes the reductive methylation of dUMP by 5,10-methylene tetrahydrofolate to generate thymidylate and dihydrofolate. TS is a critical target enzyme in cancer chemotherapy. It has been reported that IHC expression of TS could assist in predicting response of colorectal cancer patients to modulated MTX-5-FU therapy. Positive tissue: Colon cancer/Breast cancer.
Clone/PAD: 4H4B1
Immunogen: Recombinant fusion protein of human thymidylate synthase.
Specificity: Thymidylate Synthase (TS)
Reactivity: Human
Applications: Immunohistochemistry (FFPE)
Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host: Mouse
SubClass (Isotype): IgG1, kappa
Clonality: Monoclonal
Target Gene: Thymidylate Synthase
Gene ID: 7298
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 1 mL
Shipping Condition: Wet Ice
Regulatory Statement: For In Vitro Diagnostic Use.
Store in refrigerator (2–8°C). |