|
Penicillin-Streptomycin-Neomycin (PSN) Antibiotic Mixture
The antibiotics Penicillin, Streptomycin, and Neomycin are used to prevent bacterial contamination of cell cultures due to their effective combined action against gram-positive and gram-negative bacteria. Penicillin was originally purified from the fungus Penicillium and acts by interfering directly with the turnover of the bacteria cell wall and indirectly by triggering the release of enzymes that further alter the cell wall. Streptomycin was originally purified from Streptomyces griseus and Neomycin from Streptomyces fradiae. Streptomycin and Neomycin act by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria. Life Technologies offers a variety of antibiotics and antimycotics for cell culture applications.
This solution contains 5 mg of penicillin, 5 mg of streptomycin, and 10 mg of neomycin per ml in 0.85% saline.
Validated Application: Prevention of Cell Culture Contamination
Agent: Neomycin,
Streptomycin,
Penicillin
Form: Liquid
Reagent Type: Antibiotic
Concentrated: 100 X
Product Size: 100 mL
Shipping Condition: Dry Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in freezer (-5 to -30°C). |