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Cytokeratin 5/6 Mouse Monoclonal Antibody (clone D5/16B4), 2ndGen Predilute
This monoclonal antibody reacts with Cytokeratin 5/6, and reacts weakly with Cytokeratin 4. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheloid mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody to distinguish benign ductal hyperplasias from non-invasive neoplastic proliferations. Positive tissue: Skin.
Clone/PAD: D5/16B4
Immunogen: Purified Cytokeratin 5 and 6
precificity: Cytokeratin 5&6. Weak reactivity with Cytokeratin 4.
Reactivity: Human
Applications: Immunohistochemistry (FFPE)
Pretreatment: Epitope Retrieval: Required (EDTA, pH 8), Enzyme Digestion: Not required
Expected Staining Pattern: Cytoplasmic
Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host: Mouse
Target Gene: Cytokeratin 5/6
Gene ID: 140446, 3852, 3853, 3854
Label or Dye: Unconjugated
Dilution: 2ndGen Predilute Antibody
Product Size: 6 mL
Shipping Condition: Wet Ice
Regulatory Statement: For In Vitro Diagnostic Use.
Store in refrigerator (2–8°C). |