|
Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor 647 Conjugate
Close
PRODUCT FAMILY INFORMATION
MAPK Antibodies, Proteins, Inhibitors, & Assays
Offering hundreds of premium quality antibodies, enzymes, activity assays, and small molecule inhibitors for MAPK signaling research
EMD Millipore offers hundreds of premium quality antibodies, enzymes, activity assays, and small molecule inhibitors for MAPK signaling research. All EMD Millipore products are based on the expertise of Upstate, Chemicon, and Calbiochem.
» More…
Flow Cytometry Kits & Antibodies
Millipore's Milli-Mark and FlowCellect brands include fluorescent conjugated antibodies and multiparameter kits for cellular analysis. Designed, optimized, and validated for flow.
FlowCellect Kits are EMD Millipore's proprietary multiparameter flow cytometry kits for cellular analysis. We’ve taken the guesswork out of assay development so you can focus on your results. Each kit provides a unique combination of directly conjugated antibodies and/or fluorescent dyes and protein reporters to monitor changes in protein expression and post-translational modification using flow. The kits also contain complete buffer sets, protocols and pre-defined gate settings. They are fully optimized for "plug-and-play" cellular analysis on Guava EasyCyte and other flow cytometry instruments. In addition, EMD Millipore's line of Milli-Mark fluorescent conjugated antibodies are specifically designed, optimized and validated for flow, exhibit superior signal-to-noise ratios, and eliminate the need for a secondary antibody.
» More…
Species Reactivity Key Applications Host Format Antibody Type
H FC Rabbit AlexaFluor®647 Polyclonal Antibody
Description:
Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Milli-Mark
Specificity:
Antibody recognizes MAPK1/2. C-terminus.
Molecular Weight:
43 kDa Calculated
Epitope:
C-terminus
Immunogen:
KLH-conjugated linear peptide corresponding to rat MAPK 1/2 at the C-terminus.
Background Information:
The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called MAPK1 and MAPK2, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or MAPK1/2. The MAPK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of MAPK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand.
View All »
Species Reactivity:
Human
Species Reactivity Note:
Tested and passed on Human.
Control:
Jurkat cells
Quality Assurance:
Evaluated by flow cytometry using Jurkat cells
Purification Method:
Protein A purfied
Presentation:
Purified rabbit polyclonal antibody conjugated to Alexa Fluor 647 in PBS buffer with 15mg/mL BSA and 0.1% Sodium Azide
Storage Conditions:
Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
UniProt Number:
P21708
Entrez Gene Number:
NP_059043
Gene Symbol:
MAPK1
p38
ERK
P42MAPK
ERK2
p40
PRKM1
p41mapk
PRKM2
MAPK2
p42-MAPK
p41
|