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STATPAK, Anti-STAT (1, 2, 3, 5A, 5B) Miniature Set
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REFERENCES
Performance of a pilot-scale packed bed reactor for perchlorate reduction using a sulfur oxidizing bacterial consortium.
Amber R Boles,Teresa Conneely,Robert McKeever,Paul Nixon,Klaus R Nüsslein,Sarina J Ergas (2012) Biotechnology and bioengineering.109
Long-term pathologic consequences of acute irritant-induced asthma.
Naoya Takeda,Karim Maghni,Sylvie Daigle,Jocelyne L'Archevêque,Lucero Castellanos,Wisam Al-Ramli,Jean-Luc Malo,Qutayba Hamid (2009) The Journal of allergy and clinical immunology.124
Changes in glucose transport and protein kinase Cbeta(2) in rat skeletal muscle induced by hyperglycaemia.
Y Kawano,J Rincon,A Soler,J W Ryder,L A Nolte,J R Zierath,H Wallberg-Henriksson (1999) Diabetologia.42
Differential effects of proinsulin C-peptide fragments on Na+, K+-ATPase activity of renal tubule segments.
Y Ohtomo,T Bergman,B L Johansson,H Jörnvall,J Wahren (1998) Diabetologia.41
Species Reactivity Key Applications Host Format Antibody Type
H, M EMSA, IP, WB, ICC Rabbit null null
Description:
STATPAK, Anti-STAT (1, 2, 3, 5A, 5B) Miniature Set
Promotional Text:
Special Offer on Antibodies! Click Here!
Trade Name:
Upstate (Millipore)
Species Reactivity:
Human
Mouse
Quality Assurance:
routinely evaluated in western blot, immunoprecipitation, EMSA or immunocytochemistry
UniProt Number:
P42224
P52630
P40763
P42229
P51692
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Entrez Gene Number:
NM_007315.2
NM_139266.1
Gene Symbol:
STAT1
ISGF-3
STAT91
DKFZp686B04100
Components:
Anti-STAT1, Catalog #06-501-MN
Anti-STAT2, Catalog #06-502-MN
Anti-STAT3, Catalog #06-596-MN
Anti-STAT5A, Catalog #06-553-MN
Anti-STAT5B, Catalog #06-554-MN
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Electrophoretic Mobility Shift Assay
Immunoprecipitation
Western Blotting
Immunocytochemistry
Entrez Gene Summary:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
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UniProt Summary:
FUNCTION: SwissProt: P51692 # Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
SIZE: 787 amino acids; 89866 Da
SUBUNIT: Forms a homodimer or a heterodimer with a related family member. Binds NR3C1 (By similarity). Interacts with NCOA1, NMI and SOCS7.
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity). Note=Translocated into the nucleus in response to phosphorylation |