产品参数： Sequence: Gly-Arg-Gly-Asp-Asn-Pro MW: 614.6 Purity: ≥97% (HPLC) Appearance: Lyophilized solid. Solubility: Soluble in water (>50mg/ml). Long Term Storage: -20°C 产品说明： Induces apoptosis in various cell types and cell lines at 1mM by a mechanism involving cellular uptake and possible direct stimulation of procaspase-3 autoprocessing. Does not induce apoptosis in the breast cancer line MCF-7, in which there is a functional deletion of the procaspase-3 gene. Contains the motif RGD (Arg-Gly-Asp) which is found in many integrin ligands. Inhibits cell adhesion of COS-7 cells to fibronectin 80-90% at 1mM. 在各种细胞凋亡和细胞线在1毫米的机制涉及细胞吸收和可能的直接刺激procaspase-3自动处理。并不引起细胞凋亡在乳腺癌行mcf 7,其中有一个功能缺失的procaspase-3基因。包含主题RGD(arg甘胺酸asp)这是发现在许多整合素配体。抑制细胞粘附的因为7细胞纤连蛋白80 - 90%至1毫米。
