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Product Specification
Alternative Name:Caspase family inhibitor (fluoromethylketone)
Sequence:Z-Val-Ala-Asp(OMe)-fluoromethylketone
Formula:C22H30N3O7F
MW:467.5
CAS:187389-52-2
Purity:≥95%
Appearance:White to off-white solid.
Solubility:Soluble in DMSO (>10mg/ml), dimethyl formamide (7mg/ml) or 100% ethanol (1.3mg/ml).
Application:Irreversible, cell permeable, broad spectrum caspase inhibitor. Limited Fas-induced mouse liver damage and apoptosis to <1%, at a dose of 50µmol/kg. At 50µM, abrogated 7-hydroxystaurosporine and etoposide-induced apoptosis in HL60 cells.
Long Term Storage:-20°C
Use/Stability:Stable for up to 1 year after receipt when stored at -20°C. Stock solutions should be divided into aliquots and stored at -20°C for up to 1 month.
Handling:Keep cool and dry. |