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AIP (autocamtide-2-related inhibitory peptide) is a highly specific and potent inhibitor of CaM kinase II. This peptide is derived from the CaM kinase II substrate autocamtide-2 (BML-P101) but alanine is substituted for threonine at the 9-position. AIP at 1 µM completely inhibited CaM kinase II but did not affect PKC, PKA, CaMKIV and other brain extract kinases. A cell-permeable, myristoylated version is available (BML-P212).
Product Specification
Alternative Name:Autocamtide-2-related inhibitory peptide
Sequence:Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu
MW:1498.0
Purity:97%
Long Term Storage:-20°C |