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Fluorogenic substrate specific for cathepsin K, among other cathepsin family members. This substrate is also cleaved by granzyme A, thrombin, tryptase, trypsin, and kallikreins. Ex.: 365 nm, Em.: 440 nm, although the following Ex/Em can also be used: 355,380/450,460. This substrate is useful for inhibitor screening and kinetic analysis. Also available: fluorogenic calibration standard AMC (BML-KI144).
Product Specification
Alternative Name:Z-Gly-Pro-Arg-AMC
Sequence:Z-Gly-Pro-Arg-AMC•HCl [Z=Cbz=Benzyloxycarbonyl; AMC=7-amino-4-methylcoumarin]
MW:637.7
Long Term Storage:-20°C |