A-803467 is a potent and selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8 which is preferentially expressed on sensory neurons. IC50 for human Nav1.8=8.0 nM (140 nM for rat). It attenuates neuropathic and inflammatory pain in various animal models. Product Specification Formula:C19H16ClNO4 MW:357.8 CAS:944261-79-4 Purity:98% Appearance:White solid. Solubility:Soluble in DMSO (15mg/ml) or 100% ethanol (2mg/ml).
