Binds to rabbit platelet PAF receptors with high affinity. Inhibits PAF-induced platelet aggregation in rabbits (IC50=7.7 µM), bronchoconstriction in guinea-pigs, hypotension in rats and lethality in mice. Inhibits endotoxin-induced gastrointestinal damage (known to be due to PAF). Does not inhibit PAF-induced contraction of guinea pig lung parenchymal strips. Clinically useful spasmolytic agent for the control of increased tone or motility of the gut. Product Specification Alternative Name:Otilonium bromide MW:563.6 CAS:26095-59-0 Purity:98% Long Term Storage:-20°C
