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Menadione
IDO inhibitor
Cytotoxic in various cell lines. Induces apoptosis via elevation of peroxide and superoxide radical levels. Affects gap-junctional intercellular communication by mediation of tyrosine phosphorylation.Inhibitor of indoleamine 2,3-dioxygenase (IDO) with an IC50 of ~1µM.
Product Specification
Alternative Name: Vitamin K3, 2-Methyl-1,4-naphthoquinone
Formula: C11H8O2
MW: 172.2
CAS: 58-27-5
MI: 14: 5831
RTECS: QL9100000
Purity: ≥98% (HPLC)
Appearance: Off-white to yellow crystalline solid.
Hazard: HARMFUL.
Solubility: Soluble in 96% ethanol (16mg/ml) or DMSO (1mg/ml); almost insoluble in water.
Long Term Storage: Ambient
Handling: Protect from light. |