6BIO

6BIO
Inibitor of phosphoinositide-dependent kinase 1 and GSK
Inhibitor of phosphoinositide-dependent kinase 1 (PDK1). Potent, reversible and ATP-competitive inhibitor of glycogen synthase kinase-3α/β (GSK-3α/β) (IC50=5nM). Maintains self-renewal and pluripotency in embryonic stem cells via activation of Wnt in vitro. Promotes proliferation and dedifferentiation in cardiomyocytes.
Product Specification
Formula: C16H10BrN3O2
MW: 356.2
CAS: 667463-62-9
Purity: ≥98%
Appearance: Dark red solid.
Hazard: IRRITANT.
Solubility: Soluble in DMSO.
Long Term Storage: -20°C
Handling: Protect from light.