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Zoledronic acid
Acid sphingomyelinase inhibitor
Inhibitor of osteoclastic bone resorption. Prevents osteoporosis and skeletal fractures, particularly in patients with multiple myeloma or prostate cancer. Also used to treat hypercalcemia.Inhibition of acid sphingomyelinase (aSMase) with an IC50 5µm.
Product Specification
Alternative Name: 1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid, CGP 42446
Formula: C5H10N2O7P2 . H2O
MW: 272.1 . 18.0
Source: Synthetic.
CAS: 165800-06-6
MI: 14: 10187
Purity: ≥98% (HPLC)
Appearance: White to off-white powder.
Solubility: Soluble in 0.1N NaOH. Sparingly soluble in water.
Long Term Storage: -20°C |