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Nutlin-3
Inhibitor of p53/MDM2 interaction
(+/-) -Nutlin-3 is an inhibitor of p53/MDM2 interaction (IC50=0.09µM).
Product Specification
Alternative Name: (±)-4-[4,5-bis-(4-Chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazole-1-carbonyl]-piperazin-2-one
Formula: C30H30Cl2N4O4
MW: 581.5
CAS: 548472-68-0
Purity: ≥98% (HPLC)
Appearance: White to off-white crystalline solid.
Hazard: IRRITANT.
Solubility: Soluble in methanol, 100% ethanol, DMSO, dimethyl formamide or acetonitrile; sparingly soluble in a 1:10 solution of ethanol:PBS, pH 7.2.
Long Term Storage: -20°C
Use/Stability: Stable for at least one year after receipt when stored at -20°C. We do not recommend storing the aqueous solution for more than one day. |