Cobalt (III) Protoporphyrin IX chloride

Cobalt (III) Protoporphyrin IX chloride
Heme oxygenase activator
The ability of cobalt ions to induce heme oxygenase (HO) activity in liver cells was first reported almost 30 years ago. Cobalt protoporphyrin IX (CoPP) was later shown to be a substrate for HO, now identified as the inducible isoform HO-1 (heast shock protein 32; hsp32). CoPP has been shown to down-regulate various cytochrome P450 isoforms and various mechanisms of action have been attributed to CoPP and other metalloporphyrins.
Product Specification
Formula: C34H32CoN4O4 . Cl
MW: 654.5
CAS: 102601-60-5
Purity: ≥95% (TLC)
Identity: Identity determined by UV/VIS, NMR and MS.
Appearance: Dark purple solid.
Hazard: HARMFUL.
Solubility: Soluble in basic aqueous solutions at pH between 8.5-9.0. Once in solution pH can be adjusted to physiological pH.
Long Term Storage: -20°C
Handling: Protect from light and moisture.