Protoporphyrin IX (free acid) Guanylyl cyclase activator Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Product Specification Alternative Name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid Formula: C34H34N4O4 MW: 562.6 CAS: 553-12-8 MI: 14: 7897 Purity: ≥97% (HPLC) Identity: Identity determined by NMR. Appearance: Purple to dark brown solid. Hazard: IRRITANT. Solubility: Soluble in conc. HCl, DMSO (10mg/ml) or 100% ethanol (10mg/ml). Long Term Storage: -20°C Use/Stability: Make solutions fresh daily. Handling: Protect from light. |