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Echinomycin
HIF-1 inhibitor
Antitumor antibiotic. Powerful, selective inhibitor of nucleic acid synthesis in vitro. Potent inhibitor of hypoxia-inducible factor 1 (HIF-1) DNA binding activity. Induces apoptosis. Displays antibacterial, antifungal and antiviral activities.
Product Specification
Alternative Name: Quinomycin A
Formula: C51H64N12O12S2
MW: 1101.3
Source: Isolated from Streptomyces sp. (MST-AS5446).
CAS: 512-64-1
MI: 14: 3497
RTECS: JW5250000
Purity: ≥98% (HPLC)
Identity: Identity determined by 1H-NMR.
Appearance: White to off-white solid.
Hazard: MAY BE MUTAGENIC.
TOXIC.
Solubility: Soluble in 100% ethanol, dimethyl formamide or DMSO; insoluble in water.
Long Term Storage: -20°C
Handling: Hygroscopic. |