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Proteasome inhibitor I (aldehyde)
Replaces Prod. #: BML-ZW8410
Cell permeable inhibitor of the 26S proteasome (MCP; multicatalytic proteinase complex) in HT4 cells. Causes accumulation of ubiquitinylated proteins in neuronal cells. Prevents the activation of NF-κB in response to TNF-α or okadaic acid (Prod. No. ALX-350-003) through inhibition of IκBα degradation.
Product Specification
Alternative Name: Z-IE(OtBu)AL-CHO, Z-Ile-Glu(OtBu)-Ala-Leu-CHO, PSI
Sequence: Z-Ile-Glu(OtBu)-Ala-Leu-CHO
Formula: C32H50N4O8
MW: 618.8
Purity: ≥95% (TLC)
Appearance: White powder.
Solubility: Soluble in 100% ethanol (30mg/ml), DMSO (30mg/ml) or methanol (50mg/ml).
Long Term Storage: -20°C
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