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Ac-DMQD-CHO
Caspase-3 inhibitor
Replaces Prod. #: BML-P418
Reversible, aldehyde inhibitor of caspase-3 and related cysteine proteases. Exhibits high selectivity for caspase-3 over -1, -4, -6, and -7. Sequence is based on baculovirus p35 protein inhibitor site of cleavage. Together with the caspase-6 inhibitor Ac-VEID-CHO (Prod. No. ALX-260-062) this inhibitor has been used to dissect the pathway of caspase activation in Fas-stimulated Jurkat cells.
Product Specification
Alternative Name: Caspase-3 inhibitor (aldehyde)
Sequence: Ac-Asp-Met-Gln-Asp-CHO
Formula: C20H31N5O10S
MW: 533.6
Formulation: Lyophilized.
Peptide Content: 70-90%.
Purity: ≥96% (HPLC)
Appearance: White powder.
Solubility: Soluble in DMSO or distilled water.
Long Term Storage: -20°C
Use/Stability: Stock solutions should be divided into aliquots and stored at -20°C.
Handling: Keep cool and dry. |