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Z-LE(OMe)HD(OMe)-FMK
Caspase-9 inhibitor
Irreversible, cell permeable inhibitor of caspase-9. The carboxyl groups are OMe ester form to enhance cell permeability. If purified enzyme is used, esterase should be added for the hydrolysis of the ester groups.
Product Specification
Alternative Name: Caspase-9 inhibitor (fluoromethylketone)
Sequence: Z-Leu-Glu(OMe)-His-Asp(OMe)-fluoromethylketone
Formula: C32H43FN6O10
MW: 690.7
Formulation: TFA salt.
Purity: ≥95% (HPLC)
Appearance: Off-white to tan solid.
Solubility: Soluble in DMSO (20mM).
Long Term Storage: -20°C
Use/Stability: Stock solutions should be stored in aliquots at -20°C.
Handling: Very hygroscopic.
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