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Z-YVAD(OMe)-FMK
Inhibitor of caspase-1 and -4
Irreversible, cell permeable inhibitor of caspase-1. Inhibits also caspase-4.
Product Specification
Alternative Name: Caspase-1 inhibitor (fluoromethylketone)
Sequence: Z-Tyr-Val-Ala-Asp(OMe)-fluoromethylketone
Formula: C31H39FN4O9
MW: 630.7
Purity: ≥98% (TLC)
Appearance: White to off-white powder.
Solubility: Soluble in DMSO.
Long Term Storage: -20°C
Use/Stability: Stock solutions should be divided into aliquots and stored at -20°C.
Handling: Packaged under inert gas.
Background / Technical Information: The carboxyl groups are OMe ester forms to enhance cell permeability. If purified enzyme is used, esterase should be added for the hydrolysis of the ester groups. |