|
Z-IE(OMe)TD(OMe)-FMK
Caspase and granzyme inhibitor
Irreversible, cell permeable inhibitor of caspase-8 and granzyme B. Inhibits also caspase-10.
Product Specification
Alternative Name: Caspase-8 inhibitor (fluoromethylketone), Granzyme B inhibitor (fluoromethylketone)
Sequence: Z-Ile-Glu(OMe)-Thr-Asp(OMe)-fluoromethylketone
Formula: C30H43FN4O11
MW: 654.7
Purity: ≥90% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO.
Long Term Storage: -20°C
Use/Stability: Store stock solutions in aliquots at -20°C.
Handling: Packaged under inert gas.
Background / Technical Information: We recommend a final concentration of 2µM for inhibiting caspase activity in Jurkat cell culture. The optimal doses may vary for different cells and culture conditions |