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Z-D(OMe)E(OMe)VD(OMe)-FMK
Inhibitor of caspase-3 and -7
Irreversible, cell permeable inhibitor of caspase-3 and -7.
Product Specification
Alternative Name: Caspase-3 inhibitor (fluoromethylketone), Caspase-7 inhibitor (fluoromethylketone)
Sequence: Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone
Formula: C30H41FN4O12
MW: 668.7
Formulation: Lyophilized.
Purity: ≥95% (TLC)
Solubility: Soluble in DMSO (20mM) or dimethyl formamide.
Long Term Storage: -20°C
Use/Stability: Stable for 1 year after receipt when stored at -20°C.
Handling: Packaged under inert gas. After reconstitution, prepare aliquots and store at -20°C.
Background / Technical Information: We recommend a final concentration of 2-10µM for inhibiting caspase activity in cell culture. The optimal doses may vary for different cells and culture conditions |