human BMP-4

BMP-4, human recombinant
A protein involved in bone and cartilage development
Product Overview
Alternate Names / Synonyms: human BMP-4, BMP-4, BMP4, BMP 4, h-BMP-4, rh-BMP-4, recombinant human BMP-4, recombinant BMP-4, BMP
Gene Symbol: BMP 4
Accession #: P12644
Gene ID: 652
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized powder
Molecular Weight: 13.0 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: BioVision’s recombinant human BMP-4 is biologically active. The ED₅₀ as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.
Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-4 produced from E. coli is a 13 kDa monomeric, non-glycosylated, polypeptide chain containing 116 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.