|
TGF-beta1, human recombinant
A protein that controls proliferation, cellular differentiation, & other functions in most cells
Product Overview
Alternate Names / Synonyms: Human TGF-beta1, TGF-beta1, TGF beta1, TGFbeta1, h-TGF-beta1, rh-TGF-beta1, recombinant human TGF-beta1, recombinant TGF-beta, TGF
Gene Symbol: TGFB1
Accession #: P01137
Gene ID: 7040
Source: CHO cells
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from Sodium Citrate, pH3.5 buffer
Molecular Weight: 25.0 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by the ability of TGF-β1 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is <0.05 ng/ml, corresponding to a specific activity of >2 x 10⁷ units/mg.
Reconstitution Instructions: Reconstitution in water to a concentration of 50 ug/ml (e.g., 5 ug/100 ul) will yield a solution of 1 mM citrate buffer (pH 3.5). The solution can then be stored at 4°C for 1 month. It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at –20°C.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: TGF-β1 (Transforming Growth Factor-β1) is a member of the superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-β1 is a 25.0 kDa protein containing two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |