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sRANK Ligand, human recombinant
Immune signaling facilitator
Product Overview
Alternate Names / Synonyms: Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf, hRANKL2.
Gene Symbol: OPGL
Accession #: O14788
Gene ID: 8600
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from 5 mM Tris, pH 7.6 + 75 mM NaCl
Molecular Weight: 20.0 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of IL-8 production by human PBMC is <10 ng/ml.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg /ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Human RANK (receptor activator of NF-kB) is a member of the TNFR family, identified as a dentritic cell membrane protein. Human soluble RANK Ligand is a soluble 20.0 kDa polypeptide, comprising the TNF homologous region of RANKL (176 amino acid residues).
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |