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M-CSF, human recombinant
A hematopoietic growth factor
Product Overview
Alternate Names / Synonyms: Macrophage Colony stimulating Factor, CSF-1, Lanimostim, MCSF, MGC31930, M-CSF,
Gene Symbol: M-CSF
Accession #: P09603
Gene ID: 1435
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and then lyophilized from 5 mM Tris, pH 8.0 + 80 mM Arginine.
Molecular Weight: 36.8 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine M-NSF-60 cells is <5.0 ng/ml, corresponding to a specific activity of ≥2 x 10⁵ units/mg.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-0.5 mg/ml. The solution can then be diluted into other aqueous buffers
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: Macrophage Colony stimulating Factor (M-CSF) is produced by various cell types, including fibroblasts, microphages, and endothelial cells. M-CSF is involved in both the development and function of monocytes/microphages. Recombinant human M-CSF is a 36.8 kDa homodimeric protein containing two 159 amino acid polypeptide subunits.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |