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IL-32 alpha, human recombinant
A cytokine that induces immune cells to secrete TNF-α
Product Overview
Alternate Names / Synonyms: NK4TAIFTAIFaTAIFbTAIFc, TAIFd, IL-32beta, IL-32alpha, IL-32δ, IL-32γ, IL32
Gene Symbol: IL32- α
Accession #: P24001
Gene ID: 9235
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from 50 mM NaP, pH 7.5.
Molecular Weight: 14.9 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: N/A
Endotoxin Level: <0.1 ng/μg
Biological Activity: Human IL-32 α activity is measured via the dose-dependent induction of TNF-α in the human THP-1 monocytic cell line.
Reconstitution Instructions: It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: Human IL-32 α is one of approximately 6 splice variants of a gene cloned from the human lung carcinoma stable transfectant, A549-Rβ. IL-32 α has been shown to induce IL-8, TNF-α, and MIP-2 production from human & mouse macrophage cell lines. It is up-regulated in activated T- & NK-cells, and IFN-g-treated epithelial cells. Human recombinant IL-32 α produced in E. coli is a 131 amino acid non-glycosylated polypeptide with a molecular mass of 14.9 kDa.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |