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IL-17F, human recombinant
A proinflammatory cytokine produced by activated T cells
Product Overview
Alternate Names / Synonyms: Human IL-17E, IL-17E, IL 17E, IL 17E, h-IL-17E, rh-IL-17E, recombinant human IL-17E, recombinant IL-17, IL-17, interluekin-17
Gene Symbol: IL24
Accession #: Q96PD4
Gene ID: 112744
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from a concentrated solution (1 mg/ml) containing 20 mM phosphate buffer (ph 7.4).
Molecular Weight: 30.1 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by the dose-dependent induction of IL-6 in NIH-3T3 cells was found to be approximately 10 ng/ml, corresponding to a specific activity of 1.0 x 10⁵ IU/mg.
Reconstitution Instructions: The lyophilized IL-17F can be reconstituted in water to a concentration of 0.1-1.0 µg/µl. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: IL-17Fis a member of the IL-17 family of structurally-related cytokines. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F stimulates proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant human IL-17F is a 30.1 kDa consisting of two 134 amino acid polypeptide chains.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |