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IL-13, rat recombinant
A mediator of allergic inflammation and disease
Product Overview
Alternate Names / Synonyms: NC300, ALRH, BHR1, P600, IL-13
Gene Symbol: IL13
Accession #: P42203
Gene ID: 116553
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized with no additives
Molecular Weight: 12.7 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: ≥95%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells was typically 2-6 ng/ml.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having similar structural features and functional characteristics as IL-4, but only shares ~30% homolog with the IL-4 sequence. IL-13 inhibits IL-1β, IL-6, IL-8, and TNF-α resulting in anti-inflammatory effects on monocytes and macrophages. IL-13 also induces B cells to proliferate and modulating TH2 cell development. Recombinant rat IL-13 is an 11.9 kDa protein containing 109 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |