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CD40Ligand/TRAP, human recombinant
A protein primarily expressed on activated T cells and involved in immune functions
Product Overview
Alternate Names / Synonyms: human CD40Ligand/TRAP, CD40 Ligand/TRAP, h-CD40Ligand/TRAP, rh-CD40Ligand/TRAP, recombinant human CD40Ligand/TRAP, CD40 Ligand, TRAP, recombinant CD40 Ligand/ TRAP
Gene Symbol: CD40-L
Accession #: P29965
Gene ID: 959
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from 10 mM Sodium Phosphate, pH 7.5
Molecular Weight: 16.3 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: Determined by the stimulation of IL-12 induction by human peripheral blood mononuclear cells (PBMC) and the stimulation of IL-8 induction by human PBMC. The expected ED₅₀ for this effect is 5-10 ng/ml. Note: results may vary with PBMC donors.
Reconstitution Instructions: Reconstitute in 5-10 mM Sodium Phosphate (pH 7.5) to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: CD40 Ligand (CD40L/TRAP) is a type II membrane protein that effectuates the helper function of T cells on resting B cells. BioVision’s Human soluble CD40 Ligand is a 16.3 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |